Aim to study the neuromuscular entrapment in the arm due to variant coracobrachialis and brachialis muscles. 100 upper limbs of 50 donated embalmed cadavers (45 males & 5 females) of age group ranging from 70 to 80 years were dissected in the department of Anatomy at K.J. Somaiya Medical College, Sion, Mumbai, INDIA. The neuromuscular entrapment in the arm due to variant coracobrachialis and brachialis muscles was observed in 2 specimens. The photographs of the variations were taken for proper documentation and ready reference. The neuromuscular entrapment in the arm due to variant coracobrachialis and brachialis muscles was observed in 2 specimens. We observed an entrapment of brachial artery and median nerve by coracobrachialis and brachialis muscles. The median nerve and the brachial artery passed through the coracobrachialis muscle in the right arm and also an accessory slip of the brachialis muscle originated from anteromedial surface of the shaft of humerus and got inserted into the medial epicondyle of the humerus. The accessory slip of the brachialis muscle passed over the brachial artery and the median nerve. The neuromuscular entrapment in the arm due to variant coracobrachialis and brachialis muscles may have some mechanical advantages and disadvantages during the movement of elbow joint. The knowledge of such variations were important for medical fraternity such as surgeons, orthopaedicians, neurologists, radiologists and physiotherapist for dealing with injuries or operations around the elbow joint.