During routine dissection of an adult male cadaver in the department of Anatomy at K. J. Somaiya Medical College, Sion, Mumbai, INDIA, the formation of right median nerve by multiple lateral roots were observed. The finding was noted after thorough and meticulous dissection of the upper limbs of both sides (axilla, arm, forearm and palm). Out of the four roots forming the anomalous median nerve, three were from lateral cord and one from medial cord of brachial plexus. However, the distribution of the anomalous median nerve was normal in arm, forearm and palm. The arterial pattern in the arm (axillary and brachial arteries) was also normal. The photographs of the variations were taken for proper documentation. The median nerve and its roots are close to the axillary vein, which is used as the most cranial limit for axillary lymph node dissection, a procedure used in treating certain tumours, such as breast carcinoma and melanoma.The variations in the formation, course & distribution of median nerve are clinically important for surgeons, orthopaedicians and anaesthetists performing pain management therapies on the upper limb. These variations are compared with the earlier data & it is concluded that variations in branching pattern of cords of brachial plexus are a rule rather than exception. A lack of awareness of variations with different patterns might complicate surgical repair and may cause ineffective nerve blockade.