Accomplishments

Study of endometrial histopathology in patients with abnormal uterine bleeding in a tertiary care Centre.


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Category
Articles
Publisher
Editor, Ijmacr
Publishing Date
01-Mar-2023
volume
6
Issue
2
Pages
430-437

Introduction: Abnormal uterine bleeding (AUB) is one of the commonest presenting complaints in females of varying age groups. AUB is defined as change in frequency of menstruation, duration of flow or amount of blood loss. It can be caused by various inflammatory, benign or malignant lesions. Micro scopic examination of the endo metrium aids in the diagnosis of AUB. We did this study to analyse the various histopathological patterns of endometrium in AUB and to observe the incidence of various pathologies in women of different age groups. Materials and methods: This was a retrospective study done in Department of Pathology on samples received by procedures like D & C, endo metrial biopsy of patients complaining of AUB over a period of 3 years from 2019-2021. This his to mor phology of the endo metrium was studied. The analysis was done in the form of percentages and proportions and represented as tables where necessary. Results: We studied a total of 271 samples. Maximum samples were received from perimenopausal females (45.86%, n=122). Iatrogenic endometrium was seen in 27% cases (n=72). Proliferative endometrium was seen in 18.42 % (n=49) cases. Secretory endo metrium was seen in 22.55 % (n=60) cases. Basal endometrium was seen in 1.12 % cases (n=3). Hyper plasia without atypia was seen in 13.15 % (n=35) cases. Hyperplasia with atypia was seen in 0.75 % (n=2) cases. Endometrial carcinoma was seen in 3.38% (n=9) cases. 6.76 % samples (n=18) were inadequate to opine. 1.87 % samples (n=5) showed products of conception. Endo metrial polyp was seen in 5.63% (n=15) cases. 1.12% cases (n=3) showed menstrual endometrium. In the reproductive age group (<40 years), normal cyclical endo metrium was most commonly seen on his to patho logy. Peri menopausal females (41-50 years) had normal cyclical endo metrium followed by iatrogenic endo metrium and hyper plasias. Mali gnancies were most commonly seen in the post – Meno pausal (>51 years) age group.