During routine dissection for undergraduate first MBBS students an entrapment of the median nerve and the brachial artery in between the two separate heads of the biceps brachii muscle was found in the right upper limb of a 70 year old male donated embalmed cadaver in the department of Anatomy of K.J.Somaiya Medical College, Sion, Mumbai, INDIA. The unusual separate short and long heads of the biceps brachii were observed. The short head originated from the tip of the coracoid process of the scapula. The long head originated from the supraglenoid tubercle of the scapula. The short head of the biceps brachii muscle got inserted into the radial tuberosity of the radius separately. The long head got inserted into the radial tuberosity and bicipital aponeurosis. The brachial artery and the median nerve ran in between the two heads throughout their course in the arm upto the cubital fossa. The musculocutaneous nerve was absent and all the muscles of the front of the arm were supplied by the median nerve. There were no associated arterial variation seen in the specimen. The left upper limb of the cadaver was normal. The photographs of the variations were taken for proper documentation and ready reference. Topographical anatomy and variations of the bicephs brachii muscle is clainically important for surgeons, orthopaedicians, radiologists and anaesthetists performing pain management therapies.