During routine dissection of undergraduate First MBBS students a variation was found in the right upper limb of a 70 year old male donated embalmed cadaver in the department of Anatomy of K.J.Somaiya Medical College, Sion, Mumbai, India. The third head of biceps brachii was supplied by the median nerve. The third head was taking origin from the anterolateral surface of the shaft of the humerus. The third head joined with the other two heads and form a common tendon which got inserted into the radial tuberosity of the radius and bicipital aponeurosis. The musculocutaneous nerve was absent and all the muscles of the front of the arm were supplied by median nerve. The third head was also supplied by the median nerve. There was no associated arterial variation seen in the specimen. The variation was unilateral and the left upper limb of the cadaver was normal. The photographs of the variations were taken for proper documentation and ready reference. Topographical Anatomy and variations of the biceps brachii muscle is clinically important for surgeon, Orthopaedician, Radiologist and Anaesthetist performing pain management therapies.