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A case series of generalized lichenoid drug eruption due to anti-tubercular drugs: Treated with immunosuppressant’s while continuing anti-tubercular therapy


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Category
Articles
Authors
Publisher
Wolters Kluwer - Medknow
Publishing Date
01-Jun-2022
volume
8
Issue
1
Pages
23-28

The spectrum of tuberculosis-associated cutaneous adverse drug reactions (ADRs) is wide and includes Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and generalized lichenoid drug eruption (LDE). LDE constitutes less than 10% of the total incidence of anti-tubercular drug induced cutaneous ADRs. In any type of drug reaction there is a prompt need of withdrawal of suspected drugs and institution of aggressive treatment of ADRs with proper control of underlying primary disease. Herein, we present a case series of five cases of generalized LDE due to anti tubercular therapy (ATT), in whom cutaneous lesions were managed with oral immunosuppressants while continuing ATT.